Microemulsions are liquid solutions of water, oil and amphiphile that are thermodynamically stable and optically isotropic. They have become novel drug delivery systems that allow controlled or sustained release of medication for parenteral, ocular, topical, oral, percutaneous and transdermal administration. Microemulsions are among the best choices for novel drug delivery systems due to their enhanced drug solubilization, extended shelf life and ease of preparation and administration. Microemulsions differ from typical emulsions in that they have low viscosity, transparency and more accurately, thermodynamic stability. This review article's goal is to talk about using microemulsions. a succinct summary and explanation, together with details on the composition, nature and effects of additives, pressure and temperature on the phase behaviour of mixtures.

A member of the Piperaceae family of plants, betel (Piper betle) has long been used as a mouth freshener, wound healer, stimulant and preventive against cataracts and bleeding. Ayurvedic doctors frequently employ betel leaf extract as an aphrodisiac, laxative, adjuvant and flavouring. In addition to avoiding fever, ulcers, nosebleeds and eye infections, it enhances taste and appetite. Saponins, flavonoids, polyphenols, triterpenoids, essential oils (carvacrol, eugenol, chavicol, chavibetol and estragole), sesquiterpenes, sugar and starch are among the chemicals found in betel. According to studies, piper betle possesses bioactivity as an antiproliferative, hepatoprotective, analgesic, antibacterial, antimicrobial and anti-inflammatory chemical. It was found that the wonderful plant betel leaf (Piper betle), which is employed in many fields, has many uses and advantages. India's betel leaf growing industry is broad. Because of its antibacterial, antifungal, antioxidant and antiseptic qualities, betel leaves are used medicinally. Apart from its well-known medical applications, betel leaf has numerous other uses in both ancient and contemporary science.

The present study aimed at the in-vitro comparative study of anthelmintic activity of aqueous extracts of seeds of Vitis vinnifera, Punica granatum and mixed. The seeds were extracted separately with distilled water by maceration method. The various concentrations of the extract (50, 100, 200, 300, 400mg/ml) respectively were screened for their anthelmintic activity using Pheritima posthuma. The activity was similar to that of the common medication albendazole. An observable rise in anthelmintic activity occurs with increasing extract concentrations. The worms' times of paralysis (P) and death (D) were measured as part of the investigation. Aqueous extract of Vitis vinnifera, Punica granatum and mixed showed anthelmintic activity but mixed extract was more efficient anthelmintic activity against Indian earthworms.Using a one-way ANOVA, the findings were determined to be statistically significant (P<0.0001).