The usage of turmeric in Indian medicine has been widespread since ancient times. A case study was carried out in order to know the perception and use of turmeric during COVID-19 among faculty and students at the college. The findings revealed that 75% of the respondents knew the binomial name of turmeric is Curcuma longa and 68% of them respondents knew that it belongs to the ginger family Zingiberaceae. 96% of participants agreed that the active element, curcumin, has been associated with reduced symptoms of many inflammation-driven conditions and could help diminish the swelling and irritation produced by allergic rhinitis. 97% of the participants responded they had recommended turmeric to others to lead a healthy lifestyle. Most respondents knew that turmeric has numerous health benefits, like reducing inflammation, healing internal injuries and helping to ward off flu during the winter season. Studies indicate that Turmeric is an essential ingredient in traditional Indian cuisine.
Velu Vijaya*, Baskar Muthu, Balan Karunai Selvi, Mariappan Uma Maheswari.
The present research aims to design and characterize the nabumetone ethosomes for enhanced drug delivery. The main objective is to improve the solubility of BCS class II drug nabumetone by ethosomal formulation and to improve bioavailability. Formulation of ethosomalgel by avoiding first-pass metabolism to overcome the side effects of gastrointestinal bleeding. Ethosomes can be formulated by hot method using ethanol, phospholipids, cholesterol and propylene glycol. Carbopol-934 acts as a gelling agent. The evaluation of ethosomal gel includes particle size determination, zeta potential, entrapment efficiency, drug content, in vitro drug release and kinetics release studies. The optimized formulation exhibits Z - an average of 390.6nm and -4.96nm of particle size and zeta potential respectively. In vitro drug release studies are performed using egg membranes in phosphate buffer, more than 90% of the drug can be released in 12 hours. The kinetics release studies of zero order, Higuchi model and Korsmeyer-Pappas model refer to the process of constant drug release from a drug delivery system independent of concentration. The regression value of this study is 0.99. Thus, the result of the current study indicates a promising potential of ethosomal gel as an alternative to the conventional form. Further, the studies are to avoid hepatic first-pass metabolism and enhance bioavailability and biocompatibility.
C. Srinivasan* and E. Abraham Theodore Rajaselwin.